HES130/0.4：具有更适宜的分子量大小和分布，具有良好的安全性和快速的初始容量效力，扩容效应可达100%，稳定维持4-6小时;等容血液置换，可维持血容量至少6小时。能快速经肾脏清除：机体清除率高，24小时几乎完全排出体外， 即使重复给药亦无血浆积蓄;更大的推荐使用剂量：每天最大用量50ml/kg体重，可以连续给药数天。安全性高：对凝血功能影响很小;过敏反应发生率极低，一般为0.058%;对肾功能无损害，只要有尿产生，即使严重肾功能损伤的病人，也可放心使用; 研究表明其安全性与人血白蛋白相当，2004年1月在欧洲已被批准可以用于两岁以下儿童。

　　HES130/0.4: With more appropriate molecular weight and distribution, it has sound safety level and fast initial effect. The expansion effect can reach 100% and maintain stable for 4-6 hours. For equal blood volume replacement, the blood volume can be maintained for at least 6 hours. It can be quickly cleared by the kidney. With high body clearance rate, it can be almost completely removed from the body in 24 hours. No plasma accumulation even with repeated administration. Greater recommended dose. At maximum daily dosage of 50ml/kg body weight, it can be administered continuously for several days. High safety and little effect on blood coagulation. Incidence of allergic reactions is extremely low, usually 0.058%. No damage to renal function. As long as urine can be generated, it can be safely used even on those patients with serious kidney injury. Research shows its safety level is equivalent to that of human serum albumin. In January 2004 it was approved in EU to be used on infants less than two years old.

　　除满足日常临床需求外，在突发大量人员伤亡事件、战争及地震等自然灾害的情况下，HES制剂的需求尤为迫切。人血浆在无电、缺水的情况下，保存时间短，且存在血型配型问题，不便使用，该产品可常温保存，无需配型，在上述情况中是最佳急救输血用品。汶川特大地震发生后，该产品在国家紧急采购药品名单中列第一位。

　　In addition to daily clinical usage, HES preparations are in great demand during large scale emergencies such as accident, war and natural disaster. On these occasions, human plasma has short storage life due to power and water shortages and mandatory blood type compatibility also makes it inconvenient to use. While in comparison HES preparations can be stored at room temperature and there is no specific requirement on blood type compatibility, making it the best choice for emergency blood supply. Immediately after Wenchuan earthquake in 2008, it was ranked as the top priority in the purchasing list of national emergency medicines.